Early stage lymph node positive cervical cancer treated with laterally extended parametrectomy (LEP)
Introduction: In 2003, we published our preliminary experience with the use of an operative technique (laterally extended parametrectomy, the LEP procedure) without adjuvant therapy, in the treatment of 29 stage IB, cervical cancer patients with pelvic lymph node metastases. In our present paper, by...
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| Dokumentumtípus: | Könyv része |
| Megjelent: |
Szegedi Tudományegyetem Állam- és Jogtudományi Kar
Szeged
2012
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| Sorozat: | Ünnepi e-könyv : Herczeg János professzor 70. születésnapjára
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| Kulcsszavak: | Méhnyakrák - diagnosztika, Méhnyakrák - kezelés, Nőgyógyászat - terápia |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/84683 |
| LEADER | 02552naa a2200229 i 4500 | ||
|---|---|---|---|
| 001 | acta84683 | ||
| 005 | 20240409120616.0 | ||
| 008 | 240409s2012 hu o 0|| eng d | ||
| 020 | |a 978 963 306 154 1 | ||
| 040 | |a SZTE Egyetemi Kiadványok Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Ungár László | |
| 245 | 1 | 0 | |a Early stage lymph node positive cervical cancer treated with laterally extended parametrectomy (LEP) |h [elektronikus dokumentum] / |c Ungár László |
| 260 | |a Szegedi Tudományegyetem Állam- és Jogtudományi Kar |b Szeged |c 2012 | ||
| 300 | |a 216-228 | ||
| 490 | 0 | |a Ünnepi e-könyv : Herczeg János professzor 70. születésnapjára | |
| 520 | 3 | |a Introduction: In 2003, we published our preliminary experience with the use of an operative technique (laterally extended parametrectomy, the LEP procedure) without adjuvant therapy, in the treatment of 29 stage IB, cervical cancer patients with pelvic lymph node metastases. In our present paper, by an extended recruiting period, with a completed 5 years follow up, we studied the outcome of LEP operations, used with the same indications. Methods: In 70 out of 106 LEP-Wertheim operated patients, no adjuvant treatment was used. In 36 patients, where histology suggested tumor spread beyond the threshold of our surgery, adjuvant chemo-radiotherapy was advised. 5 years follow up was completed (without lost for follow up) for the whole cohort of patients. Results: In 70 patients treated by LEP procedure alone, the overall 5-years survival was 91.4%. For those 36 patients, who were excluded due to disease spread above study criteria, 5 years survival was 44%. Complications in 10% of cases necessitated a second operation. Apart from transient hyper continence and one case of permanent incontinence, no severe quality of life consequence of the operation was observed. Conclusions: Our results suggest that in 2/3rd of pelvic lymph node positive, stage IB cervical cancer cases surgery alone could provide equal or better survival ( without the toxicity of chemoradiotherapy), than any kind of multimodality treatment alternatives. LEP procedure should be considered a treatment option for stage IB cervical cancer patients with pelvic lymph node metastases. | |
| 650 | 4 | |a Orvos- és egészségtudomány | |
| 650 | 4 | |a Klinikai orvostan | |
| 695 | |a Méhnyakrák - diagnosztika, Méhnyakrák - kezelés, Nőgyógyászat - terápia | ||
| 700 | 0 | 1 | |a Tarnai László |e aut |
| 856 | 4 | 0 | |u http://acta.bibl.u-szeged.hu/84683/1/unnepi_ekonyv_herczeg_janos_2012_216-228.pdf |z Dokumentum-elérés |