Successful Treatment of Multiple Basaliomas with Bleomycin-based Electrochemotherapy A Case Series of Three Patients with Gorlin-Goltz Syndrome. /

Gorlin-Goltz syndrome is a rare multisystemic disease, characterized by numerous basal cell carcinomas. The ideal approach for patients with the syndrome would be a treatment with a high cure rate, minimal scarring, short healing time and mild side-effects. Electrochemo-therapy is a novel therapeuti...

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Elmentve itt :
Bibliográfiai részletek
Szerzők: Kis Erika
Baltás Eszter
Kinyó Ágnes
Varga Erika
Nagy Nikoletta
Gyulai Rolland Péter
Kemény Lajos
Oláh Judit Magdolna
Dokumentumtípus: Cikk
Megjelent: 2012
Sorozat:ACTA DERMATO-VENEREOLOGICA 92 No. 6
doi:10.2340/00015555-1361

mtmt:1965286
Online Access:http://publicatio.bibl.u-szeged.hu/21403
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520 3 |a Gorlin-Goltz syndrome is a rare multisystemic disease, characterized by numerous basal cell carcinomas. The ideal approach for patients with the syndrome would be a treatment with a high cure rate, minimal scarring, short healing time and mild side-effects. Electrochemo-therapy is a novel therapeutic option that ablates tumours with electrical current and simultaneously administered anticancer drugs. Three patients with Gorlin-Goltz syndrome were treated with electrochemotherapy using intravenous bleomycin. Clinical response was obtained in 98 (99%) of the lesions, 86 (87%) of them showed complete response. In 2 tumours, regression was confirmed with histological examination. Long-term cosmetic results were excellent. We consider electrochemotherapy to be an additional tool in the therapeutic armamentarium for Gorlin-Goltz syndrome, and suggest using it as early as possible in selected patients to avoid disfiguring scarring. 
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700 0 1 |a Kinyó Ágnes  |e aut 
700 0 1 |a Varga Erika  |e aut 
700 0 1 |a Nagy Nikoletta  |e aut 
700 0 1 |a Gyulai Rolland Péter  |e aut 
700 0 1 |a Kemény Lajos  |e aut 
700 0 1 |a Oláh Judit Magdolna  |e aut 
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