Successful Treatment of Multiple Basaliomas with Bleomycin-based Electrochemotherapy A Case Series of Three Patients with Gorlin-Goltz Syndrome. /
Gorlin-Goltz syndrome is a rare multisystemic disease, characterized by numerous basal cell carcinomas. The ideal approach for patients with the syndrome would be a treatment with a high cure rate, minimal scarring, short healing time and mild side-effects. Electrochemo-therapy is a novel therapeuti...
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Dokumentumtípus: | Cikk |
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2012
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Sorozat: | ACTA DERMATO-VENEREOLOGICA
92 No. 6 |
doi: | 10.2340/00015555-1361 |
mtmt: | 1965286 |
Online Access: | http://publicatio.bibl.u-szeged.hu/21403 |
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245 | 1 | 0 | |a Successful Treatment of Multiple Basaliomas with Bleomycin-based Electrochemotherapy |h [elektronikus dokumentum] : |b A Case Series of Three Patients with Gorlin-Goltz Syndrome. / |c Kis Erika |
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490 | 0 | |a ACTA DERMATO-VENEREOLOGICA |v 92 No. 6 | |
520 | 3 | |a Gorlin-Goltz syndrome is a rare multisystemic disease, characterized by numerous basal cell carcinomas. The ideal approach for patients with the syndrome would be a treatment with a high cure rate, minimal scarring, short healing time and mild side-effects. Electrochemo-therapy is a novel therapeutic option that ablates tumours with electrical current and simultaneously administered anticancer drugs. Three patients with Gorlin-Goltz syndrome were treated with electrochemotherapy using intravenous bleomycin. Clinical response was obtained in 98 (99%) of the lesions, 86 (87%) of them showed complete response. In 2 tumours, regression was confirmed with histological examination. Long-term cosmetic results were excellent. We consider electrochemotherapy to be an additional tool in the therapeutic armamentarium for Gorlin-Goltz syndrome, and suggest using it as early as possible in selected patients to avoid disfiguring scarring. | |
700 | 0 | 1 | |a Baltás Eszter |e aut |
700 | 0 | 1 | |a Kinyó Ágnes |e aut |
700 | 0 | 1 | |a Varga Erika |e aut |
700 | 0 | 1 | |a Nagy Nikoletta |e aut |
700 | 0 | 1 | |a Gyulai Rolland Péter |e aut |
700 | 0 | 1 | |a Kemény Lajos |e aut |
700 | 0 | 1 | |a Oláh Judit Magdolna |e aut |
856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/21403/1/3689.pdf |z Dokumentum-elérés |