Hemp Seed Oil Effects on Female Rats Fed a High-Fat Diet and Modulating Adiponectin, Leptin, and Lipid Profile
Background: The prevalence of obesity is increasing dramatically worldwide. Obesity injuries have been linked to the alteration of many health biomarkers in humans. Consuming a 2.5:1 ratio of omega-6 and omega-3 helps to restore standard health biomarkers. Hemp, the non-psychoactive variety of Canna...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2023
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| Sorozat: | AGRICULTURE-BASEL
13 No. 2 |
| Tárgyszavak: | |
| doi: | 10.3390/agriculture13020449 |
| mtmt: | 34719581 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/29777 |
| Tartalmi kivonat: | Background: The prevalence of obesity is increasing dramatically worldwide. Obesity injuries have been linked to the alteration of many health biomarkers in humans. Consuming a 2.5:1 ratio of omega-6 and omega-3 helps to restore standard health biomarkers. Hemp, the non-psychoactive variety of Cannabis Sativa L., has a long history of being used as a source of food, fiber, and medicine. One of its attractive features is the favorable omega-6:omega-3 ratio found in its seed oil (HSO), making it a promising functional food for mitigating obesity-related injuries. Methods: A total of 84 female Wistar rats were randomly allocated into four groups. Two control groups (n = 21 each) were fed with a standard diet supplemented with 10% HSO. Two other equivalent groups consumed a high-fat diet, and one was supplemented with 10% HSO. Rats were euthanized from each group at 5, 10, or 15 weeks to measure body weight change, food intake, and several health biomarkers. Results: The results demonstrated that body weight gain and triglycerides were lower (p ≤ 0.05) for the control group supplemented with HSO compared with the other groups. Adiponectin concentration was lower (p ≤ 0.05) in both the control and high-fat treated groups. Other biomarkers were comparable among treatment diets. Conclusion: Our results suggest the usefulness of HSO supplementation for the overall health status. |
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| Terjedelem/Fizikai jellemzők: | 9 |
| ISSN: | 2077-0472 |