Hemp Seed Oil Effects on Female Rats Fed a High-Fat Diet and Modulating Adiponectin, Leptin, and Lipid Profile
Background: The prevalence of obesity is increasing dramatically worldwide. Obesity injuries have been linked to the alteration of many health biomarkers in humans. Consuming a 2.5:1 ratio of omega-6 and omega-3 helps to restore standard health biomarkers. Hemp, the non-psychoactive variety of Canna...
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Dokumentumtípus: | Cikk |
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2023
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Sorozat: | AGRICULTURE-BASEL
13 No. 2 |
Tárgyszavak: | |
doi: | 10.3390/agriculture13020449 |
mtmt: | 34719581 |
Online Access: | http://publicatio.bibl.u-szeged.hu/29777 |
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040 | |a SZTE Publicatio Repozitórium |b hun | ||
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100 | 2 | |a Abu Ghazal Tasneem | |
245 | 1 | 0 | |a Hemp Seed Oil Effects on Female Rats Fed a High-Fat Diet and Modulating Adiponectin, Leptin, and Lipid Profile |h [elektronikus dokumentum] / |c Abu Ghazal Tasneem |
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490 | 0 | |a AGRICULTURE-BASEL |v 13 No. 2 | |
520 | 3 | |a Background: The prevalence of obesity is increasing dramatically worldwide. Obesity injuries have been linked to the alteration of many health biomarkers in humans. Consuming a 2.5:1 ratio of omega-6 and omega-3 helps to restore standard health biomarkers. Hemp, the non-psychoactive variety of Cannabis Sativa L., has a long history of being used as a source of food, fiber, and medicine. One of its attractive features is the favorable omega-6:omega-3 ratio found in its seed oil (HSO), making it a promising functional food for mitigating obesity-related injuries. Methods: A total of 84 female Wistar rats were randomly allocated into four groups. Two control groups (n = 21 each) were fed with a standard diet supplemented with 10% HSO. Two other equivalent groups consumed a high-fat diet, and one was supplemented with 10% HSO. Rats were euthanized from each group at 5, 10, or 15 weeks to measure body weight change, food intake, and several health biomarkers. Results: The results demonstrated that body weight gain and triglycerides were lower (p ≤ 0.05) for the control group supplemented with HSO compared with the other groups. Adiponectin concentration was lower (p ≤ 0.05) in both the control and high-fat treated groups. Other biomarkers were comparable among treatment diets. Conclusion: Our results suggest the usefulness of HSO supplementation for the overall health status. | |
650 | 4 | |a Általános orvostudomány | |
650 | 4 | |a Egészségtudományok | |
700 | 0 | 1 | |a Subih Hadil S. |e aut |
700 | 0 | 1 | |a Obeidat Belal S. |e aut |
700 | 0 | 1 | |a Awawdeh Mofleh S. |e aut |
856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/29777/1/agriculture-13-00449.pdf |z Dokumentum-elérés |