Are the metal identity and stoichiometry of metal complexes important for colchicine site binding and inhibition of tubulin polymerization?

Quite recently we discovered that copper(II) complexes with isomeric morpholine-thiosemicarbazone (morph-TSCs) hybrid ligands show good cytotoxicity in cancer cells and that the molecular target responsible for this activity might be...

Elmentve itt :
Bibliográfiai részletek
Szerzők: Besleaga Iuliana
Raptová Renáta
Stoica Alexandru-Constantin
Milunović Miljan N.M
Zalibera Michal
Bai Ruoli
Igaz Nóra
Reynisson Johannes
Csontné Kiricsi Mónika
Enyedy Éva Anna
Rapta Peter
Hamel Ernest
Arion Vladimir
Dokumentumtípus: Cikk
Megjelent: 2024
Sorozat:DALTON TRANSACTIONS 53 No. 29
Tárgyszavak:
doi:10.1039/D4DT01469C

mtmt:35081780
Online Access:http://publicatio.bibl.u-szeged.hu/34348
Leíró adatok
Tartalmi kivonat:Quite recently we discovered that copper(II) complexes with isomeric morpholine-thiosemicarbazone (morph-TSCs) hybrid ligands show good cytotoxicity in cancer cells and that the molecular target responsible for this activity might be...
Terjedelem/Fizikai jellemzők:12349-12369
ISSN:1477-9226