Interactions of IOX1, a histone demethylase inhibitor, with essential metal ions, albumin, and its clay-based nanoformulation

Herein, the chemical properties of 5-carboxy-8-hydroxyquinoline (IOX1), a histone lysine demethylase KDM4 inhibitor, were comprehensively characterized in aqueous solution, including its complex formation equilibria with essential metal ions such as...

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kovács Hilda
Dömötör Orsolya
Giricz Anett
Igaz Nóra
Szőke Krisztina
Bocz Csenge
Csontné Kiricsi Mónika
Szerlauth Adel
Ormos Réka
Szilágyi István
Enyedy Éva Anna
Dokumentumtípus: Cikk
Megjelent: 2026
Sorozat:DALTON TRANSACTIONS 55 No. 16
Tárgyszavak:
doi:10.1039/D6DT00242K

mtmt:37064492
Online Access:http://publicatio.bibl.u-szeged.hu/39974
Leíró adatok
Tartalmi kivonat:Herein, the chemical properties of 5-carboxy-8-hydroxyquinoline (IOX1), a histone lysine demethylase KDM4 inhibitor, were comprehensively characterized in aqueous solution, including its complex formation equilibria with essential metal ions such as...
Terjedelem/Fizikai jellemzők:6462-6479
ISSN:1477-9226